Synthetic cathinones are a class of lab-made stimulants chemically related to substances found in the khat plant (Catha edulis Forsk). They are β-keto phenethylamines, similar in structure to amphetamine and methamphetamine.
Key Characteristics
- Derivatives of naturally occurring cathinone, the main psychoactive ingredient in khat
- β-Keto moiety in their structure, similar to amphetamine
- Internationally controlled substances include cathinone, methcathinone, cathine, and pyrovalerone
- Listed in Schedule I, III, and IV of the 1971 Single Convention on Psychotropic Substances
- Appeared in drug markets in the mid-2000s
Effects
- Produce similar effects to common stimulants like methamphetamine or MDMA
- Often reported to produce stronger effects that wear off quicker than MDMA
- Pentylone, a synthetic cathinone, has been found in “brick-shaped” ‘Nike tick’ MDMA pills
Chemical Structure
- Related to cathinone, a psychoactive principal in khat
- β-Keto analogues of corresponding phenethylamines
- Includes several substances used as active pharmaceutical ingredients (API) of medicinal products
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